Corporate Overview
Founded in 2006, Cempra Pharmaceuticals is a clinical-stage pharmaceutical company focused on developing antibacterials to meet critical medical needs. Two lead antibacterial products, both in the treatment of infectious diseases, address the urgent and increasing need for new treatments targeting drug-resistant bacterial infections in both the hospital and the community. Cempra is committed to developing commercially and medically differentiated products that provide a treatment alternative to address patient needs. The company is also utilizing its series of proprietary lead compounds from our novel macrolide library for uses such as the treatment of chronic inflammatory diseases, endocrine diseases and gastric motility disorders.
Addressing the need for novel antibiotics that act against drug-resistant bacteria.
Antibiotic resistance has been a rising threat to human health for several years. Effectiveness of many antibacterial agents has declined worldwide limiting physicians' options to treat serious infections. Antibiotic drug resistance has a significant impact on mortality and contributes heavily to healthcare system costs worldwide. The World Health Organization has stated that antibiotic resistance is one of the greatest healthcare challenges for the future. Cempra is focused on developing solutions to this problem and addressing the future needs of patients.
Cempra has two antibiotic candidates, solithromycin (CEM-101) and TAKSTA™ (CEM-102, sodium fusidate), in clinical trials. Both target the growing problem of antimicrobial resistance.
Solithromycin is a novel fluoroketolide that is active against macrolide-resistant bacteria and is more active than azithromycin or clarithromycin against most macrolide-susceptible bacteria. It is the first macrolide since azithromycin to have the potential to be administered both orally and intravenously (IV). Orally-administered solithromycin recently completed Phase II clinical trials in patients with community-acquired pneumonia and the IV formulation is being evaluated in a Phase I clinical trial in healthy volunteers.
TAKSTA (sodium fusidate) is an agent with a long history of safety and efficacy outside the U.S. It is active against gram-positive pathogens, including both hospital- and community-acquired methicillin-resistant S. aureus (MRSA). Cempra's loading dose regimen innovation is designed to maximize efficacy and bacterial coverage while minimizing resistance development. TAKSTA has completed Phase II clinical trials in acute bacterial skin and skin structure infections and we are planning Phase III clinical trials for the same indication and a Phase II trial for prosthetic joint infections.
Led by an accomplished management team dedicated to shape the future of the company and the industry.
Cempra is led by a management team with extensive drug development and commercialization experience in the area of anti-infectives. The company is supported by a world-class Scientific Advisory Board comprised of renowned industry and infectious disease experts and a committed syndicate of experienced investors.
Founded in 2006, Cempra Pharmaceuticals is a clinical-stage pharmaceutical company focused on developing antibacterials to meet critical medical needs. Two lead antibacterial products, both in the treatment of infectious diseases, address the urgent and increasing need for new treatments targeting drug-resistant bacterial infections in both the hospital and the community. Cempra is committed to developing commercially and medically differentiated products that provide a treatment alternative to address patient needs. The company is also utilizing its series of proprietary lead compounds from our novel macrolide library for uses such as the treatment of chronic inflammatory diseases, endocrine diseases and gastric motility disorders.Addressing the need for novel antibiotics that act against drug-resistant bacteria.
Antibiotic resistance has been a rising threat to human health for several years. Effectiveness of many antibacterial agents has declined worldwide limiting physicians' options to treat serious infections. Antibiotic drug resistance has a significant impact on mortality and contributes heavily to healthcare system costs worldwide. The World Health Organization has stated that antibiotic resistance is one of the greatest healthcare challenges for the future. Cempra is focused on developing solutions to this problem and addressing the future needs of patients.
Cempra has two antibiotic candidates, solithromycin (CEM-101) and TAKSTA™ (CEM-102, sodium fusidate), in clinical trials. Both target the growing problem of antimicrobial resistance.
Solithromycin is a novel fluoroketolide that is active against macrolide-resistant bacteria and is more active than azithromycin or clarithromycin against most macrolide-susceptible bacteria. It is the first macrolide since azithromycin to have the potential to be administered both orally and intravenously (IV). Orally-administered solithromycin recently completed Phase II clinical trials in patients with community-acquired pneumonia and the IV formulation is being evaluated in a Phase I clinical trial in healthy volunteers.
TAKSTA (sodium fusidate) is an agent with a long history of safety and efficacy outside the U.S. It is active against gram-positive pathogens, including both hospital- and community-acquired methicillin-resistant S. aureus (MRSA). Cempra's loading dose regimen innovation is designed to maximize efficacy and bacterial coverage while minimizing resistance development. TAKSTA has completed Phase II clinical trials in acute bacterial skin and skin structure infections and we are planning Phase III clinical trials for the same indication and a Phase II trial for prosthetic joint infections.
Led by an accomplished management team dedicated to shape the future of the company and the industry.
Cempra is led by a management team with extensive drug development and commercialization experience in the area of anti-infectives. The company is supported by a world-class Scientific Advisory Board comprised of renowned industry and infectious disease experts and a committed syndicate of experienced investors.